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Blood compatibility assessments of electrospun polyurethane nanocomposites blended with megni oil for tissue engineering applications Anais da ABC (AABC)
JAGANATHAN,SARAVANA KUMAR; MANI,MOHAN P.; SUPRIYANTO,EKO.
Abstract: Tissue engineering holds as a prominent technique to repair or replace the damaged human parts to recreate its native function. In this research, a novel scaffold based on polyurethane (PU) comprising megni oil was electrospun for tissue engineering applications. The obtained polyurethane blended with megni oil nanofibers were characterized by scanning electron microscopy (SEM), fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), contact angle measurement and atomic force microscopy (AFM). Furthermore, the blood compatibility of the fabricated nanocomposites evaluated through activated prothrombin time (APTT), partial thromboplastin time (PT) and hemolysis assay to determine the anticoagulant nature. The...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Polyurethane; Megni oil; Electrospun scaffold; Blood compatibility; Tissue engineering.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300708
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Electrospun novel nanocomposite comprising polyurethane integrated with ayurveda amla oil for bone tissue engineering Anais da ABC (AABC)
JAGANATHAN,SARAVANA KUMAR; MANI,MOHAN P..
Abstract Ayurveda oil contains numerous source of biological constituents which plays an important role in reducing the pain relief caused during bone fracture. The aim of the study is to fabricate the polyurethane (PU) scaffold for bone tissue engineering added with ayurveda amla oil using electrospinning technique. Scanning Electron Microscopy (SEM) analysis showed that the fabricated nanocomposites showed reduced fiber diameter (758 ± 185.46 nm) than the pristine PU (890 ± 116.91 nm). Fourier Infrared Analysis (FTIR) revealed the existence of amla oil in the PU matrix by hydrogen bond formation. The contact angle results revealed the decreased wettability (116° ± 1.528) of the prepared nanocomposites compared to the pure PU (100° ± 0.5774). The...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Polyurethane; Ayurveda oil; Electrospun scaffold; Blood compatibility; Bone tissue engineering.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000101101
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UV induced surface modification on improving the cytocompatibility of metallocene polyethylene Anais da ABC (AABC)
JAGANATHAN,SARAVANA K.; PRASATH,MANI M..
ABSTRACT Demand for medical implants is rising day by day as the world becomes the place for more diseased and older people. Accordingly, in this research, metallocene polyethylene (mPE), a commonly used polymer was treated with UV rays for improving its biocompatibility. Scanning electron microscopy (SEM) images confirmed the formation of crests and troughs, which depicts the improvement of surface roughness of mPE substrates caused by UV etching. Accordingly, the contact angle measurements revealed that the wettability of mPE-2.5 J/cm2 (68.09º) and mPE-5 J/cm2 (57.93º) samples were found to be increased compared to untreated mPE (86.84º) indicating better hydrophilicity. Further, the UV treated surface exhibited enhanced blood compatibility as determined...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Metallocene polyethylene; UV treatment; Surface properties; Blood compatibility; Cytotoxicity properties; Biocompatible polymers.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000100195
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